ASSOCIATION BETWEEN MR ELASTOGRAPHY LIVER STIFFNESS AND HISTOLOGIC LIVER FIBROSIS IN CHILDREN AND YOUNG ADULTS WITH AUTOIMMUNE LIVER DISEASE

A study evaluated the effectiveness of MR elastography (MRE) in assessing liver fibrosis in children and young adults with autoimmune liver disease (AILD). The study included 46 patients who underwent both MRE and liver biopsy. MRE liver stiffness showed a strong positive correlation with histologic liver fibrosis (ρ = 0.68). For identifying advanced fibrosis, MRE had an AUC of 0.81, with 65.4% sensitivity and 90.0% specificity, outperforming biochemical markers APRI and FIB-4. The findings suggest that MRE is a reliable noninvasive tool for monitoring liver fibrosis severity in AILD patients.

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Quiz Fifty Seven

1 / 5

What is the primary purpose of using MR elastography in this context?

To measure liver blood flow

To assess liver stiffness and fibrosis

To detect liver tumors

To monitor liver enzyme levels

2 / 5

What type of liver disease is being investigated in this study?

Non-Alcoholic Fatty Liver Disease

Autoimmune Liver Disease

Viral Hepatitis

Alcoholic Liver Disease

3 / 5

What age group is the focus of this study?

Elderly Adults

Children and Young Adults

Middle-aged Adults

Infants

4 / 5

What is being measured in association with MR elastography liver stiffness in the study?

Bile Duct Obstruction

Histologic Liver Fibrosis

Liver Enzyme Levels

Liver Size

5 / 5

What imaging technique is used to assess liver stiffness in this study?

X-ray

CT Elastography

MR Elastography

Ultrasound Elastography

Your score is

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