ASSOCIATION OF CULPRIT LESION PLAQUE CHARACTERISTICS WITH FLOW RESTORATION POST-FIBRINOLYSIS IN ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION: AN INTRAVASCULAR ULTRASOUND-VIRTUAL HISTOLOGY STUDY

In patients with ST-segment elevation myocardial infarction (STEMI) who undergo fibrinolysis, not all achieve normal coronary flow. This study investigated the characteristics of culprit lesion plaques using virtual histology-intravascular ultrasound (VH-IVUS) in relation to baseline TIMI flow. Pre-intervention IVUS was conducted on 61 STEMI patients post-fibrinolysis, divided into TIMI 1–2 flow group (n = 31) and TIMI 3 flow group (n = 30). The study found that the external elastic membrane cross-sectional area (EEM CSA) was higher in the TIMI 1–2 group, while plaque burden and volume were similar between groups. VH-IVUS showed that the TIMI 1–2 group had a higher fibrous area, necrotic core (NC) area, and NC percentage at the minimal luminal area site. The absolute NC volume was significantly higher in the TIMI 1–2 group and was the only independent predictor of TIMI 1–2 flow, with a receiver operating characteristic curve indicating high diagnostic accuracy. The study concludes that the necrotic core component of the culprit lesion is crucial in predicting coronary flow restoration post-fibrinolysis.

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Quiz Sixty Two

1 / 5

What is the editorial comment questioning about abbreviated breast MRI?

Its availability

Whether it represents a new era for breast cancer screening

Its accuracy

Its safety

2 / 5

What disease is the focus of the screening method discussed?

Skin Cancer

Breast Cancer

Prostate Cancer

Lung Cancer

3 / 5

What does the term 'on repeat' suggest about the use of abbreviated breast MRI?

It is used in emergency situations

It is not recommended for regular use

It is used frequently or regularly

It should only be used once

4 / 5

What is the main focus of the editorial comment?

The history of breast cancer screening

The potential of abbreviated breast MRI as a new screening method

The effectiveness of traditional mammography

The cost of breast cancer screening

5 / 5

What type of MRI is being discussed in the editorial comment?

Cardiac MRI

Full-Body MRI

Abbreviated Breast MRI

Functional MRI

Your score is

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