Solitary fibrous tumors of the liver (SFTL) are rare neoplasms, and determining their malignancy risk poses a diagnostic challenge. We report the case of a 62-year-old patient who presented with an indeterminate liver lesion. Initial imaging techniques, including conventional ultrasound and computed tomography, indicated a partially fibrotic lesion, yet the precise origin and malignancy potential remained unclear. Contrast-enhanced ultrasound (CEUS) was subsequently utilized, offering critical insights by characterizing the lesion as having an extra-hepatocellular origin and suggesting malignant potential. Based on the CEUS findings, the lesion was suspected to be a cholangiocarcinoma, leading to a decision to avoid biopsy due to the risk of tumor seeding, which is especially concerning in cases with suspected malignancy. Given the uncertainty and the potential risks, the patient was recommended for surgical resection. Post-surgical histopathological examination confirmed the diagnosis of solitary fibrous tumor of the liver. This case highlights the advanced capability of CEUS in providing detailed information regarding tumor characteristics and potential malignancy, making it an effective tool in guiding the clinical management of complex liver lesions. By identifying the extra-hepatocellular nature of the tumor and hinting at malignancy, CEUS not only influenced the diagnostic process but also helped in devising a safer, more targeted treatment approach, ultimately aiding in successful treatment planning and patient care.