This study evaluates the effects of low molecular weight hyaluronic acid fragments combined with amino acids (HAAM) on facial skin rejuvenation through intradermal microinjections. Involving twenty women aged 35-64, the study used mesotherapy to administer HAAM and conducted biopsies and ultrasound exams before and three months after treatment. Histological analysis showed increased fibroblast activity, Type III collagen production, blood vessel count, and epidermal thickness. However, ultrasound data revealed no significant difference in skin thickness in various facial areas. Overall, HAAM significantly impacted the dermis of facial skin.
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