Summary
The study aimed to evaluate four ultrasound technologies for quantitatively assessing liver fat content in children, using MRI proton density fat fraction (PDFF) as a reference standard.
The prospective study included 48 children who underwent clinical abdominal MRI, and an investigational liver ultrasound was performed within a day of the MRI. Ultrasound parameters, including the attenuation coefficient and hepatorenal index (HRI), were compared with MRI PDFF.
The results indicated that both the attenuation coefficient and HRI accurately detected and quantified liver fat in the studied children. The study suggests that these ultrasound technologies could be valuable for the noninvasive assessment of liver fat in pediatric patients with nonalcoholic fatty liver disease.