Researchers at Washington University in St. Louis have developed a technique called sonobiopsy, which combines ultrasound and microbubbles to temporarily disrupt the blood-brain barrier. By doing so, RNA, DNA, and proteins from the brain can be released into the bloodstream and analyzed. This technique could allow for noninvasive biopsies for brain tumors and other brain diseases, providing valuable molecular and genetic information to aid in diagnosis and treatment decisions. The procedure is safe and has the potential to revolutionize the field of brain disease diagnosis by enabling access to genetic information without the risks of traditional brain surgery. The researchers have created a portable, handheld ultrasound probe that can be integrated into clinical workflows, making advanced diagnostics more accessible. Clinical trials are already underway to evaluate the efficacy of sonobiopsy for various applications.
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