Summary
The study aims to demonstrate the safety, efficacy, and durability of magnetic resonance (MR) imaging–guided high-intensity focused ultrasound (HIFU) as a treatment for osteoid osteoma in children and young adults.
A total of 45 patients underwent MR imaging–guided HIFU, and the primary outcomes included feasibility, safety, and clinical effectiveness, with tumor control as a secondary outcome. Results showed that all patients were discharged without treatment-related complications, and the median visual analog scale (VAS) pain score decreased significantly. Quality of life, as assessed by Functional Assessment of Cancer Therapy-Bone Pain scores, improved.
MR imaging at the 36-month follow-up demonstrated an absence of residual nidus vascularity in the majority of patients treated with MR imaging–guided HIFU. The study concludes that MR imaging–guided HIFU is a safe and effective treatment option for osteoid osteoma, suggesting its potential incorporation into routine clinical practice.
