This pilot study evaluated the feasibility and safety of using ultrasound (US) and CT fusion imaging for guiding lumbar intradiscal oxygen-ozone (O2/O3) therapy in patients with discogenic low back pain due to lumbar disc herniation (LDH). Researchers compared outcomes between a Fusion Group, where CT/US fusion imaging was used for guidance, and a Control Group, where standard CT guidance was employed. Data points collected included operative time, room utilization time, the number of CT scans required, procedural complications, and the adequacy of O2/O3 diffusion within the disc. Technical success was defined as the ability to complete the procedure as intended, reaching the targeted disc, while technical efficacy depended on the adequate intradiscal diffusion of O2/O3, confirmed by final CT scans.
In total, twelve patients were included in the study, six in each group. The Fusion Group demonstrated significantly better outcomes, with shorter room utilization time (average of 30 minutes versus 46 minutes in the Control Group) and shorter procedure time (average of 14 minutes versus 24 minutes). Additionally, the Fusion Group required fewer CT passes (an average of 2 versus 3). Both groups achieved 100% technical success and efficacy, and no complications were observed, indicating that CT/US fusion imaging can provide an effective alternative to standard CT guidance. This method may reduce radiation exposure by minimizing the number of CT passes required, thereby streamlining the procedure and enhancing patient safety. This study supports the feasibility of CT/US fusion imaging as a potentially faster, safer, and more efficient option for guiding lumbar intradiscal O2/O3 injections.
